[14] Club Deportes Santa Cruz 1-0 Deportes Iquique [9] 2022-08-15 19:00
Stadium: Estadio Municipal Joaquín Muñoz García Round: 24
Head to Head
| Chile - Primera B | 2022/04/03 16:30 | Deportes Iquique v Club Deportes Santa Cruz | D | 2-2 |
| Chile - Primera B | 2021/10/03 15:30 | Deportes Iquique v Club Deportes Santa Cruz | L | 6-1 |
| Chile - Primera B | 2021/05/30 16:00 | Club Deportes Santa Cruz v Deportes Iquique | L | 1-3 |