[14] Club Deportes Santa Cruz 1-0 Deportes Iquique [9] 2022-08-15 19:00
Stadium: Estadio Municipal Joaquín Muñoz García Round: 24
Head to Head
| Chile - Primera B | 2022/04/03 16:30 | Deportes Iquique v Club Deportes Santa Cruz | D | 2-2 |
| Chile - Primera B | 2021/10/03 15:30 | Deportes Iquique v Club Deportes Santa Cruz | L | 6-1 |
| Chile - Primera B | 2021/05/30 16:00 | Club Deportes Santa Cruz v Deportes Iquique | L | 1-3 |
Home History
| Chile - Primera B | 2022/08/08 16:30 | Barnechea v Club Deportes Santa Cruz | L | 2-0 |
| Chile - Primera B | 2022/08/01 00:30 | Club Deportes Santa Cruz v Cobreloa | D | 1-1 |
| Chile - Primera B | 2022/07/26 22:00 | Club Deportes Santa Cruz v CD Arturo Fernández Vial | W | 2-0 |
| Chile - Primera B | 2022/07/16 15:00 | Magallanes v Club Deportes Santa Cruz | D | 0-0 |
| Chile - Primera B | 2022/07/08 22:00 | Club Deportes Santa Cruz v Santiago Morning | W | 1-0 |
| Chile - Primera B | 2022/07/02 16:30 | Deportes Temuco v Club Deportes Santa Cruz | D | 1-1 |
| Chile - Primera B | 2022/06/02 19:00 | Cobreloa v Club Deportes Santa Cruz | L | 1-0 |
| Chile - Primera B | 2022/05/27 22:00 | Club Deportes Santa Cruz v Santiago Wanderers | W | 2-0 |
Away History
| Chile - Primera B | 2022/08/09 00:30 | Deportes Iquique v Santiago Morning | W | 3-1 |
| Chile - Primera B | 2022/07/31 15:00 | Magallanes v Deportes Iquique | L | 1-0 |
| Chile - Primera B | 2022/07/26 00:30 | Deportes Iquique v Puerto Montt | D | 1-1 |
| Chile - Primera B | 2022/07/15 22:00 | Deportes Temuco v Deportes Iquique | L | 3-2 |
| Chile - Primera B | 2022/07/02 01:00 | Deportes Iquique v Santiago Wanderers | W | 2-1 |
| Chile - Primera B | 2022/06/05 19:30 | Santiago Wanderers v Deportes Iquique | L | 2-0 |
| Chile - Primera B | 2022/05/29 16:30 | Deportes Iquique v Melipilla | W | 3-0 |
| Chile - Primera B | 2022/05/21 16:30 | Union San Felipe v Deportes Iquique | L | 2-0 |