[7] Resistencia FC 1-2 Guairena FC [8] 2022-08-05 21:00
Stadium: Estadio Tomas Beygon Gorea Round: 5
Referee: Juan Gabriel Benitez Home Manager: Roberto Ismael Torres Away Manager: Troadio Daniel Duarte
Head to Head
| Paraguay - Division Profesional | 2022/05/14 20:00 | Guairena FC v Resistencia FC | D | 0-0 |
| Paraguay - Division Profesional | 2022/03/05 21:00 | Resistencia FC v Guairena FC | D | 2-2 |
| Paraguay - Division Intermedia | 2019/10/20 12:00 | Resistencia FC v Guairena FC | D | 2-2 |
| Paraguay - Division Intermedia | 2019/07/07 19:00 | Guairena FC v Resistencia FC | L | 4-1 |
| Paraguay - Division Intermedia | 2018/09/09 14:00 | Guairena FC v Resistencia FC | L | 3-0 |
| Paraguay - Division Intermedia | 2018/06/02 19:00 | Resistencia FC v Guairena FC | D | 0-0 |
| Paraguay - Division Intermedia | 2017/07/02 19:00 | Guairena FC v Resistencia FC | D | 2-2 |
| Paraguay - Division Intermedia | 2017/03/26 19:30 | Resistencia FC v Guairena FC | W | 3-0 |