[11] Santiago Wanderers 0-0 La Serena [15] 2021-01-18 20:00
Stadium: Estadio Elias Figueroa Brander Round: 31
Referee: Cristian Garay Home Manager: Miguel Ramirez Away Manager: Miguel Ponce
Head to Head
| Chile - Primera Division | 2020/02/23 15:00 | La Serena v Santiago Wanderers | L | 3-0 |
| Chile - Primera B | 2019/09/14 23:00 | Santiago Wanderers v La Serena | W | 4-1 |
| Chile - Primera B | 2019/05/11 19:30 | La Serena v Santiago Wanderers | D | 0-0 |
| Chile - Primera B | 2018/09/24 21:00 | La Serena v Santiago Wanderers | D | 1-1 |
| Chile - Primera B | 2018/04/21 18:00 | Santiago Wanderers v La Serena | D | 1-1 |
| Chile - Pohár | 2016/07/17 19:00 | Santiago Wanderers v La Serena | W | 2-1 |
| Chile - Pohár | 2016/07/09 00:00 | La Serena v Santiago Wanderers | L | 3-1 |