Round: 1
| NCAAF | 2022/08/27 20:00 | Florida Memorial University Lions v Edward Waters Tigers | L | 39-34 |
| NCAAF | 2021/11/06 21:00 | Savannah State v Edward Waters Tigers | L | 24-0 |
| NCAAF | 2021/10/30 22:00 | Edward Waters Tigers v Miles Golden Bears | L | 9-16 |
| NCAAF | 2021/10/23 18:00 | Edward Waters Tigers v Central State | W | 56-19 |
| NCAAF | 2021/10/16 17:00 | Edward Waters Tigers v Kentucky Thorobreds | L | 36-76 |
| NCAAF | 2021/10/09 18:00 | Albany State Golden Rams v Edward Waters Tigers | L | 30-0 |
| NCAAF | 2021/10/02 18:00 | Morehouse College Maroon Tigers v Edward Waters Tigers | W | 13-37 |
| NCAAF | 2021/09/25 22:00 | Edward Waters Tigers v Lane College Dragons | L | 35-45 |
| NCAAF | 2021/11/06 18:00 | Clark Atlanta University v Morehouse College Maroon Tigers | L | 26-35 |
| NCAAF | 2021/10/30 18:00 | Clark Atlanta University v Benedict College | L | 21-24 |
| NCAAF | 2021/10/23 18:00 | Fort Valley State v Clark Atlanta University | L | 40-7 |
| NCAAF | 2021/10/16 19:00 | Savannah State v Clark Atlanta University | L | 49-14 |
| NCAAF | 2021/10/09 18:00 | Clark Atlanta University v Allen Yellow Jackets | W | 21-12 |
| NCAAF | 2021/10/02 18:00 | Tuskegee v Clark Atlanta University | L | 21-0 |
| NCAAF | 2021/09/25 23:00 | Albany State Golden Rams v Clark Atlanta University | L | 49-0 |
| NCAAF | 2021/09/18 16:00 | Clark Atlanta University v Shorter Hawks | L | 17-38 |