[2] Cuiabá 1-2 CA River Plate [4] 2022-04-27 22:15
Stadium: Arena Pantanal Round: 3
Referee: Cristian Garay Home Manager: Pintado Away Manager: Gustavo Diaz Dominguez
Home History
| Brazílie - Serie A | 2022/04/24 21:00 | EC Juventude v Cuiabá | W | 0-1 |
| Copa do Brasil | 2022/04/22 00:30 | Atlético GO v Cuiabá | D | 1-1 |
| Brazílie - Serie A | 2022/04/17 00:00 | Cuiabá v Fluminense | L | 0-1 |
| Copa Sudamericana | 2022/04/13 22:15 | Racing Club v Cuiabá | L | 2-0 |
| Brazílie - Serie A | 2022/04/10 21:00 | Fortaleza EC v Cuiabá | W | 0-1 |
| Copa Sudamericana | 2022/04/07 22:15 | Cuiabá v FBC Melgar | W | 2-0 |
| Brazílie - Campeonato Matogrossense | 2022/04/02 19:30 | Cuiabá v Uniao Rondonopolis | W | 4-0 |
| Brazílie - Campeonato Matogrossense | 2022/03/26 18:30 | Uniao Rondonopolis v Cuiabá | W | 2-3 |
Away History
| Uruguay - Apertura | 2022/04/23 19:00 | CA River Plate v Danubio | D | 0-0 |
| Uruguay - Apertura | 2022/04/17 21:00 | Nacional De Football v CA River Plate | D | 1-1 |
| Copa Sudamericana | 2022/04/13 22:15 | FBC Melgar v CA River Plate | L | 2-0 |
| Uruguay - Apertura | 2022/04/10 19:00 | CA River Plate v Albion FC | W | 4-1 |
| Copa Sudamericana | 2022/04/07 22:15 | CA River Plate v Racing Club | L | 0-1 |
| Uruguay - Apertura | 2022/04/03 00:00 | Defensor Sporting v CA River Plate | L | 3-2 |
| Uruguay - Apertura | 2022/03/20 19:30 | CA River Plate v Atletico Fenix Montevideo | W | 3-1 |
| Copa Sudamericana | 2022/03/16 22:15 | CA River Plate v Liverpool Montevideo | W | 2-0 |