[1] Louisville City FC 2-1 Detroit City FC [5] 2022-10-05 23:30
Stadium: Lynn Family Stadium Round: 1
Head to Head
| USA USL Championship | 2022/08/20 23:30 | Detroit City FC v Louisville City FC | W | 0-1 |
| USA - US Open Cup | 2022/05/10 23:30 | Detroit City FC v Louisville City FC | W | 3-5 |
Home History
| USA USL Championship | 2022/10/02 00:30 | Rio Grande Valley FC Toros v Louisville City FC | W | 0-1 |
| USA USL Championship | 2022/09/24 00:00 | Louisville City FC v Memphis 901 FC | L | 1-2 |
| USA USL Championship | 2022/09/17 23:30 | Louisville City FC v Loudoun United FC | W | 4-2 |
| USA USL Championship | 2022/09/10 23:00 | Pittsburgh Riverhounds v Louisville City FC | D | 0-0 |
| USA USL Championship | 2022/09/08 00:30 | Tulsa v Louisville City FC | D | 2-2 |
| USA USL Championship | 2022/09/03 23:30 | Louisville City FC v Sacramento Republic | W | 3-1 |
| USA USL Championship | 2022/08/31 23:00 | Indy Eleven v Louisville City FC | L | 2-1 |
| USA USL Championship | 2022/08/27 23:00 | Miami FC v Louisville City FC | L | 1-0 |
Away History
| USA USL Championship | 2022/10/01 22:30 | Loudoun United FC v Detroit City FC | W | 0-4 |
| USA USL Championship | 2022/09/24 23:30 | Detroit City FC v Tulsa | D | 2-2 |
| USA USL Championship | 2022/09/21 23:00 | New York Red Bulls II v Detroit City FC | D | 0-0 |
| USA USL Championship | 2022/09/17 23:30 | Detroit City FC v Tampa Bay Rowdies | W | 1-0 |
| USA USL Championship | 2022/09/11 01:00 | Colorado Switchbacks FC v Detroit City FC | W | 1-2 |
| USA USL Championship | 2022/09/03 23:30 | Detroit City FC v Indy Eleven | D | 0-0 |
| USA USL Championship | 2022/08/28 00:00 | Charleston Battery v Detroit City FC | W | 0-3 |
| USA USL Championship | 2022/08/20 23:30 | Detroit City FC v Louisville City FC | L | 0-1 |