[112] Andy Murray 6-2,6-7,6-3,3-6,4-6 Stefanos Tsitsipas [3] 2021-08-30 18:30
Stadium: Arthur Ashe Stadium Round: 23 Ground: Hardcourt outdoor
Home History
| ATP Winston-Salem | 2021/08/24 23:50 | Frances Tiafoe v Andy Murray | 7-6,6-3 |
| ATP Winston-Salem | 2021/08/22 23:45 | Noah Rubin v Andy Murray | 2-6,0-6 |
| ATP Cincinnati | 2021/08/18 15:40 | Hubert Hurkacz v Andy Murray | 7-6,6-3 |
| ATP Cincinnati | 2021/08/17 01:00 | Richard Gasquet v Andy Murray | 4-6,4-6 |
| Wimbledon | 2021/07/02 17:55 | Denis Shapovalov v Andy Murray | 6-4,6-2,6-2 |
| Wimbledon | 2021/06/30 17:10 | Oscar Otte v Andy Murray | 3-6,6-4,6-4,4-6,2-6 |
| Wimbledon | 2021/06/28 17:05 | Andy Murray v Nikoloz Basilashvili | 6-4,6-3,5-7,6-3 |
| ATP Queen's | 2021/06/17 13:00 | Matteo Berrettini v Andy Murray | 6-3,6-3 |
Away History
| ATP Cincinnati | 2021/08/21 22:00 | Alexander Zverev v Stefanos Tsitsipas | 6-4,3-6,7-6 |
| ATP Cincinnati | 2021/08/20 23:00 | Felix Auger Aliassime v Stefanos Tsitsipas | 2-6,7-5,1-6 |
| ATP Cincinnati | 2021/08/19 23:00 | Lorenzo Sonego v Stefanos Tsitsipas | 7-5,3-6,4-6 |
| ATP Cincinnati | 2021/08/19 01:00 | Sebastian Korda v Stefanos Tsitsipas | 6-7,3-6 |
| ATP Toronto | 2021/08/14 19:00 | Stefanos Tsitsipas v Reilly Opelka | 7-6,6-7,4-6 |
| ATP Toronto | 2021/08/13 16:00 | Casper Ruud v Stefanos Tsitsipas | 1-6,4-6 |
| ATP Toronto | 2021/08/12 15:00 | Karen Khachanov v Stefanos Tsitsipas | 3-6,2-6 |
| ATP Toronto | 2021/08/10 23:50 | Ugo Humbert v Stefanos Tsitsipas | 3-6,7-6,1-6 |